IVF versus IVM
Standard IVF Treatments
- Once a day for 10 days prior to the start of her period, a woman injects herself with an antagonist hormone that down-regulates her ovaries so that they will respond better to the coming stimulation.
- On Day 2 or 3 of her period, a woman must have two daily injections for a week to 10 days of a follicle-stimulating hormone to spur the production of eggs.
- By the 10th day, the follicles enlarge, indicating the maturing eggs. At this point the woman gets an injection of human chorionic gonadotropin, which triggers the egg ovulation process but fertility doctors retrieve the eggs for IVF 36 hours later prior to them being released naturally.
- On average, this standard IVF protocol yields 10 mature eggs.
What it costs
At McGill, one cycle of IVF costs $4,500 plus the drugs, which add at minimum $2,500 per cycle, depending on the age of woman and amount needed. Treatments can easily run more than $7,000.
In Vitro Maturation
- The patient contacts the clinic on Day 3 of her menstrual cycle and undergoes an ultrasound, where doctors count the number of follicles present. If there are at least 10 follicles, where the eggs reside, visible in her ovaries, a second ultrasound is scheduled.
- On Day 8 of the cycle, doctors recount the follicles and check the lining of the uterus to ensure it is at least 6 mm thick if an embryo is to be implanted. If the count holds up, the patient is given an injection to trigger the ovulation process.
- About 36 hours later, doctors collect the immature eggs from the woman's ovaries.
- The immature eggs are then submerged in a mineral-rich liquid medium that mimics the fluid of the ovarian follicles and are placed in an incubator. Most eggs mature within 24 to 48 hours.
- Mature eggs can be fertilized, or, as part of the McGill clinical trial, frozen.
What it yields
- On average, doctors can collect an average of 10 immature eggs from women with polycystic ovaries (who have abnormally high follicle counts). Data from Korea suggest that IVM on other women can yield one mature egg and three to five immature eggs.
What it costs
At McGill, one IVM cycle costs $3,975 for Canadian residents.
Source: Dr. Ri-Cheng Chian, McGill University Health Centre, Department of Obstetrics and Gynecology
- Once a day for 10 days prior to the start of her period, a woman injects herself with an antagonist hormone that down-regulates her ovaries so that they will respond better to the coming stimulation.
- On Day 2 or 3 of her period, a woman must have two daily injections for a week to 10 days of a follicle-stimulating hormone to spur the production of eggs.
- By the 10th day, the follicles enlarge, indicating the maturing eggs. At this point the woman gets an injection of human chorionic gonadotropin, which triggers the egg ovulation process but fertility doctors retrieve the eggs for IVF 36 hours later prior to them being released naturally.
- On average, this standard IVF protocol yields 10 mature eggs.
What it costs
At McGill, one cycle of IVF costs $4,500 plus the drugs, which add at minimum $2,500 per cycle, depending on the age of woman and amount needed. Treatments can easily run more than $7,000.
In Vitro Maturation
- The patient contacts the clinic on Day 3 of her menstrual cycle and undergoes an ultrasound, where doctors count the number of follicles present. If there are at least 10 follicles, where the eggs reside, visible in her ovaries, a second ultrasound is scheduled.
- On Day 8 of the cycle, doctors recount the follicles and check the lining of the uterus to ensure it is at least 6 mm thick if an embryo is to be implanted. If the count holds up, the patient is given an injection to trigger the ovulation process.
- About 36 hours later, doctors collect the immature eggs from the woman's ovaries.
- The immature eggs are then submerged in a mineral-rich liquid medium that mimics the fluid of the ovarian follicles and are placed in an incubator. Most eggs mature within 24 to 48 hours.
- Mature eggs can be fertilized, or, as part of the McGill clinical trial, frozen.
What it yields
- On average, doctors can collect an average of 10 immature eggs from women with polycystic ovaries (who have abnormally high follicle counts). Data from Korea suggest that IVM on other women can yield one mature egg and three to five immature eggs.
What it costs
At McGill, one IVM cycle costs $3,975 for Canadian residents.
Source: Dr. Ri-Cheng Chian, McGill University Health Centre, Department of Obstetrics and Gynecology
Labels: in vitro fertilization, in vitro maturation, ivf, ivm
posted by Volatto at 9:57 AM
11 Comments:
i need to come to Canada then! IVF is insanely expensive here and IVM is rarely offered. Thanks for the run-down!
What a great site! How wonderful to have someplace to come for information on infertility. I too suffered from infertility, went through IVF SIX time to come out with my beautiful daughter. We just can't afford any more tries for a sibling and it breaks my heart. Thanks for a place to get info and talk with others going through the same thing.
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Thank you very much for sharing this information with us!
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IVF in India has reached to a stage where more and more couples prefer this process. It is not just the success rate but the ease of treatment, healthy baby, way to overcome genetic disorder and much more. There is no doubt that IVF can do wonders in many complex cases and therefore it is one of the best options to go for.
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